Dept of Genetics, School of Veterinary Medicine, University of Pennsylvania
Project: Developing Retinal Therapies in Models of Retinal Degeneration
Proof of principle studies in retinal disease models have demonstrated that experimental therapies can be evaluated and transitioned into clinical trials for retinal diseases in human patients (e.g., gene therapy for LCA; CNTF via encapsulated cell based therapy technology). Dr. Aguirre will continue to use disease relevant models to develop or evaluate novel therapies that have the potential for restoring sight or preventing/slowing down the loss of vision in human patients.